389 Dutch Jews from Amsterdam and Rotterdam are committed to the camp.
The SS transfer the Dutch Jews and the majority of the Sinti and Roma to the Mauthausen concentration camp near Linz, where they perish in the quarries.
Following the arrival of two inmate transports of Polish and Jewish inmates, the systematic murder of persons afflicted with tuberculosis by means of injections begins.
On two transports under the file number "14f13", 187 sick and disabled inmates are taken to the Sonnenstein "euthanasia" killing facility in Pirna and suffocated in the gas chamber there.
The SS execute Soviet prisoners of war in the firing range of the Deutsche Ausrüstungswerke adjacent to the camp. For future shooting executions they set up a facility in an SS stable to the west of the camp. Over the course of the following two years, the members of the "SS Kommando 99" murder 8,000 Soviet prisoners of war by shooting them in the neck.
The Wehrmacht turns 2,000 Soviet prisoners of war from the Wietzendorf prisoner-of-war camp over to the SS to serve as forced labourers. A special subcamp is established within the concentration camp for Soviet prisoners of war.
A commission of "euthanasia" assessors selects Jewish inmates for extermination.
Camp Commandant Koch is transferred to Lublin. There are 7,911 inmates and 1,902 Soviet prisoners of war in the camp. The camp death toll for 1941 is 1,746. This does not include the Soviet prisoners of war, whose deaths are not recorded.